Reliability of cold agglutinin test (CAT) for the detection of patients with Mycoplasma pneumoniae pneumonia

Reliability of cold agglutinin test (CAT) for diagnosis of Mycoplasma pneumoniae pneumonia in hospitalized patients

Introduction: M. pneumoniae is one of the causative agents of primary atypical pneumonia. This infection causes 20-40% of community acquired pneumonia and is associated with an array of extrapulmonary manifestations. There is a need for a rapid diagnostic test in order to prescribe prompt and appropriate antibiotic therapy. Even though isotype specific antibody testing provides definitive diagn...

Mycoplasma pneumonia with persistent lymphadenopathy and severe cold agglutinin haemolysis

Mycoplasma pneumonia is an atypical pneumonia commonly affecting young patients with generally mild clinical course. We present a case of a 66-year-old female presenting with weight loss, night sweats and low-grade pyrexia. She acquired symptomatic haemolytic anaemia requiring blood transfusion, markedly raised erythrocyte sedimentation rate (ESR) to 114 mm/hr and extensive peri-hilar lymphaden...

Detection of Cold Agglutinin with Cross-Reactive Idiotype Produced by Pneumonie Patients

The prevalence of Mycoplasma pneumoniae infection in patients with ventilator-associated pneumonia hospitalized in intensive care unit

Background: Ventilator-associated pneumonia (VAP) is a type of hospital acquired pneumonia with the mortality rate between 27% and 76% that develops more than 48–72 h after endotracheal intubation. Possible causes leading to this infection can be Mycoplasma pneumoniae. The objective of this study was to determine the presence of Mycoplasma pneumoniae in bronchoalveolar samples of patients with ...

Transient cold agglutinin disease with mycoplasma infection.

Cold agglutinins are autoantibodies and are often present in the sera of healthy individuals. They assume importance when the thermal reactivity of these antibodies approaches body temperature. This communication describes a case of cold hemagglutinin disease with Mycoplasma pneumoniae infection detected during routine laboratory investigations. The patient was managed conservatively.